How might we build a simple, lasting, affordable shelter with local, durable materials constructed from a basic design?
How might we develop online power measurement and regulation instruments?
How might we encourage open source mechanisms for drug discovery?
How might we capture and reward indigenous knowledge within health systems?
How might we illuminate deep rural communities in the developing world?
How might we increase access to scientific knowledge in the developing world?
How might we increase transparency to address government corruption using science, technology & innovation
How might we build the capacity of developing country governments in impact evaluation?
How might we harness talents in one country to help address challenges in another?
How might we make available education anytime, anywhere for anyone?
How might we use Scientific Technological & Innovative tools to address conflicting land tenure and the tragedy of the commons?
How might we develop new adaptable grids for economies based on distributed energy production?